As filed with the Securities and Exchange Commission on June 24, 2021
Registration No. 333-

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM F-1

REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933

GH Research PLC
(Exact Name of Registrant as Specified in Its Charter)

Ireland
2834
Not applicable
(State or Other Jurisdiction of
Incorporation or Organization)
(Primary Standard Industrial
Classification Code Number)
(I.R.S. Employer
Identification Number)

GH Research PLC
28 Baggot Street Lower
Dublin 2
D02 NX43
Ireland
Tel: +353 1 437 8443
(Address, including zip code, and telephone number, including area code, of registrant’s principal executive offices)

Cogency Global Inc.
122 East 42nd Street, 18th Floor
New York, NY 10168
Tel: (800) 221-0102
(Name, address, including zip code, and telephone number, including area code, of agent for service)

Copies to:
Deanna L. Kirkpatrick
Yasin Keshvargar
Davis Polk & Wardwell LLP
450 Lexington Avenue
New York, New York 10017
Tel: (212) 450-4000
Eavan Saunders
Shane O’Donnell
Dentons Ireland LLP
Joshua Dawson House
Dawson St
Dublin 2
D02 RY95
Ireland
Tel: +353 1 582 8100
Cian McCourt
Ailish Finnerty
Arthur Cox LLP
Ten Earlsfort Terrace
Dublin 2
D02 T380
Ireland
Tel: +353 1 920 1000
Richard C. Segal
Eric Blanchard
Divakar Gupta
Cooley LLP
55 Hudson Yards
New York, NY 10001
Tel: (212) 479-6000

Approximate date of commencement of proposed sale to the public: As soon as practicable after this registration statement becomes effective.

If any of the securities being registered on this form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, check the following box. ☐

If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☒ 333-256796

If this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐

If this Form is a post-effective amendment filed pursuant to Rule 462(d) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933.
Emerging growth company. ☒

If an emerging growth company that prepares its financial statements in accordance with U.S. GAAP, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards† provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

CALCULATION OF REGISTRATION FEE

Title Of Each Class
Of Securities To Be Registered
Amount to be
Registered(1)
Proposed Maximum
Offering Price Per Share(2)
Proposed Maximum Aggregate Offering Price(1)(2)
Amount Of Registration Fee
Ordinary shares, nominal value $0.025 per share
   1,916,666
   $16.00
   $30,666,656
   $3,345.74

(1)
The 1,916,666 ordinary shares being registered pursuant to this Registration Statement are in addition to the 9,583,333 ordinary shares registered pursuant to the Registrant’s Registration Statement on Form F-1 (File No. 333-256796).

(2)
The registration fee is calculated in accordance with Rule 457(a) under the Securities Act of 1933, as amended (the “Securities Act”), based on the proposed maximum aggregate offering price. The Registrant previously paid a filing fee of $16,728.67 in connection with the filing of the Registration Statement on Form F-1, as amended (File No. 333-256796), which Registration Statement was declared effective by the Securities and Exchange Commission on June 24, 2021 and contemplated a proposed maximum offering price of $153,333,328. In accordance with Rule 462(b) under the Securities Act, an additional amount of securities having a proposed maximum aggregate offering price of $30,666,656 are hereby registered, which includes shares subject to the underwriters’ option to purchase additional shares.

The registration statement shall become effective upon filing with the Securities and Exchange Commission in accordance with Rule 462(b) under the Securities Act of 1933, as amended.

EXPLANATORY NOTE AND INCORPORATION BY REFERENCE

This Registration Statement is being filed pursuant to Rule 462(b) (“Rule 462(b)”) and General Instruction V of Form F-1, both promulgated under the Securities Act of 1933, as amended. Pursuant to Rule 462(b), the contents of the Registration Statement on Form F-1 (File No. 333-256796) of GH Research PLC (the “Registrant”), including the exhibits thereto, which was declared effective by the Securities and Exchange Commission (the “Commission”) on June 24, 2021, are incorporated by reference into this Registration Statement.

The required opinion and consents are listed on an Exhibit Index attached hereto and filed herewith.

EXHIBIT INDEX

EXHIBIT
NUMBER
 
DESCRIPTION OF EXHIBIT
 
Opinion of Dentons Ireland LLP.
 
Consent of independent registered public accounting firm.
 
Consent of Dentons Ireland LLP (included in Exhibit 5.1).
 
Power of Attorney (included on signature page to this registration statement).

*
Previously filed.
 


SIGNATURES

Pursuant to the requirements of the Securities Act, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form F-1 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Dublin, Ireland, on the 24th day of June, 2021.

 
GH RESEARCH PLC
       
 
By:
/s/ Theis Terwey
   
Name:
Theis Terwey
   
Title:
Chief Executive Officer

Pursuant to the requirements of the Securities Act, this registration statement has been signed by the following persons in the capacities and on the dates indicated.

Signature
 
Title
 
Date
         
/s/ Theis Terwey
 
Chief Executive Officer (Principal
Executive Officer)
 
June 24, 2021
Theis Terwey
         
/s/ Julie Ryan
 
Group Finance Director (Principal Financial
Officer and Principal Accounting Officer)
 
June 24, 2021
Julie Ryan
         
*
 
Managing Director, Ireland
 
June 24, 2021
Magnus Halle
         
*
 
Director
 
June 24, 2021
Florian Schönharting
         
*
 
Director
 
June 24, 2021
Spike Loy
         
*
 
Director
 
June 24, 2021
Michael Forer
         
*
 
Authorized representative in the United
States
 
June 24, 2021
Colleen A. De Vries

*By:
/s/ Julie Ryan
 
 
Julie Ryan
 
 
Attorney-in-Fact
 



Exhibit 5.1

   
 
                                                      Dentons Ireland LLP
2nd Floor
Joshua Dawson House
Dawson Street
Dublin 2
D02 RY95
Ireland

dentons.com

24 June 2021

To:
Board of Directors
GH Research plc
28 Baggot Street Lower
Dublin 2
D02 NX43
Ireland

RE: GH Research Public Limited Company – Registration Statement on Form F-1 - Exhibit 5.1

Ladies and Gentlemen

We have acted as Irish legal advisers to GH Research plc, a public limited company incorporated in Ireland with registered number 691405 (the “Company”), in connection with the Registration Statement on Form F-1 (File No. 333-256796) the “Registration Statement”, filed by the Company with the Securities and Exchange Commission (the “SEC”) on 4 June 2021 (as subsequently amended) under the Securities Act of 1933, as amended (the “Securities Act”), in connection with the offering of up to 9,583,333 new ordinary shares in the capital of the Company (the “Offering”) and the filing of a registration statement pursuant to rule 462(b) of the Securities Act (the “462(b) Registration Statement”) in connection with the offering of up to 1,916,666 additional new ordinary shares in the capital of the Company (the “Additional Ordinary Shares”).

1
INTRODUCTION

1.1
Purpose

In connection with the preparation and filing of the 462(b) Registration Statement we have been asked to provide opinions on certain matters, as set out below. We have taken instructions in this regard solely from the Company.

1.2
Defined terms and headings

In this letter:

(a)
capitalised terms used without definition in this letter or the schedules hereto have the meanings assigned to them in the Registration Statement unless a contrary indication appears; and

(b)
headings are for ease of reference only and shall not affect interpretation.

Davis Brown ► East African Law Chambers ► Eric Silwamba, Jalasi and Linyama ► Durham Jones & Pinegar ► LEAD Advogados ► Rattagan Macchiavello Arocena ► Jiménez de Aréchaga, Viana & Brause ► Lee International ► Kensington Swan ► Bingham Greenebaum ► Cohen & Grigsby ► Sayarh & Menjra ► Larraín Rencoret ► For more information on the firms that have come together to form Dentons, go to dentons.com/legacyfirms

Eavan Saunders | Peter O’Brien | Gareth Steen | Shane O’Donnell | Andrew Muckian | Mairéadh Dale | Adrian Magnus | Catriona Munro
Dentons is a global legal practice providing client services worldwide through its member firms and affiliates. Dentons Ireland LLP is a partnership authorised and regulated by the Law Society of Ireland Number F10185. Any reference to a “partner” means a person who is a partner, member, consultant or employee with equivalent standing and qualifications in one of Dentons’ affiliates. Please see dentons.com for Legal Notices.
78432906.7

 
   
 
 
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1.3
Legal Review

For the purpose of issuing this letter, we have examined such questions of law as we have considered appropriate to give the opinions set forth in this letter. We have reviewed:

(a)
the documents listed in schedule 1 (Documents) to this letter (the “Documents”);

(b)
legal searches against the Company on 24 June 2021 on the file of the Company maintained by the Registrar of Companies in Dublin, the Judgments Office of the High Court and the Central Office of the High Court (the “Searches”); and

(c)
such other corporate records of the Company as we have deemed necessary as a basis for the opinions hereinafter expressed.

1.4
Applicable Law

This letter, the opinions given in it, and any non-contractual obligations arising out of or in connection with this letter and / or the opinions given in it, are governed by, and are to be construed in accordance with, the laws of Ireland (meaning Ireland exclusive of Northern Ireland) and relate only to Irish law as applied by the Irish courts. In particular:

(a)
we have not investigated the laws of any country other than Ireland (meaning Ireland exclusive of Northern Ireland) and we express no opinion in this letter on the laws of any jurisdiction other than Ireland (meaning Ireland exclusive of Northern Ireland)  and we assume that no foreign law effects any of the opinions given below. It is assumed that no foreign law which may apply to the matters contemplated by the 462(b) Registration Statement, the Offering, the Company, any document or any other matter contemplated by any document would or might affect this letter and / or opinions given in it; and

(b)
we do not undertake or accept any obligation to update this letter and / or opinions given in it to reflect subsequent changes in Irish law or factual matters.

1.5
Assumptions

(a)
The opinions given in this letter are given on the basis of each of the assumptions set out in schedule 2 (Assumptions) to this letter.

(b)
The opinions given in this letter are strictly limited to the matters stated in paragraph 2 (Opinion) below and do not extend, and should not be read as extending, by implication or otherwise, to any other matters.

2
OPINION

Subject to paragraph 1 (Introduction), the other matters set out in this letter and its schedules and to any matters not disclosed to us, it is our opinion that, the Additional Ordinary Shares, when issued in accordance with the terms of the 462(b) Registration Statement, will have been duly authorised and will be validly issued, fully paid and will be non-assessable (which term means that no further sums are required to be paid by the holders thereof in connection with the issue of such Additional Ordinary Shares).

 
   
 
 
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3
EXTENT OF OPINIONS

3.1
We express no opinion as to any agreement, instrument or other document other than as specified in this letter or as to any liability to tax or duty which may arise or be suffered as a result of or in connection with the Offering or the transactions contemplated thereby.

3.2
This letter only applies to those facts and circumstances which exist as at today’s date and we assume no obligation or responsibility to update or supplement this letter to reflect any facts or circumstances which may subsequently come to our attention, any changes in laws which may occur after today, or to inform the addressee of any change in circumstances happening after the date of this letter which would alter our opinion.

4
DISCLOSURE AND RELIANCE

4.1
This letter is addressed to you in connection with the 462(b) Registration Statement. We consent to the filing of this letter with the SEC as an exhibit to the 462(b) Registration Statement and any amendments thereto.  We also hereby consent to the reference to Dentons Ireland LLP in the 462(b) Registration Statement. In giving such consent, we do not thereby admit that we are in the category of persons whose consent is required under Section 7 of the Securities Act or the rules and regulations thereunder.

4.2
Other than for the purpose set out in the prior paragraph, this letter may not be relied upon, or assigned, for any purpose, without our prior written consent, which may be granted or withheld in our discretion.

Yours faithfully

/s/ Dentons Ireland LLP

DENTONS IRELAND LLP

 
   
 
 
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Schedule 1

Documents

1.
A copy of the Registration Statement.

2.
A draft of the 462(b) Registration Statement filed with the SEC on 24 June 2021.

3.
The results of the Searches.

4.
A copy of the certificate of incorporation of the Company dated 29 March 2021.

5.
A copy of the constitution of the Company adopted by the resolution of the shareholders of the Company on 27 May 2021 (the “Constitution”).

6.
A copy of the constitution of the Company exhibited to the Registration Statement and proposed to be effective immediately prior to completion of the Offering (the “Completion Constitution”).

7.
A copy of the resolutions of the shareholders of the Company dated 18 June 2021 approving, conditional on the SEC ruling the initial public offering of the ordinary shares of the Company effective under the terms of the Registration Statement, amongst other things, the adoption of the Completion Constitution, the redemption of the 25,000 A ordinary shares of €1.00 each from Florian Schönharting out of the proceeds of the Offering and subsequent cancellation, the conversion of 5,923,079 Series A preferred shares of $0.01 each into 5,923,079 ordinary shares of $0.01 each, the conversion of 25,379,047 Series B preferred shares of $0.01 each into 25,379,047 ordinary shares of $0.01 each and the subsequent consolidation of the ordinary shares of $0.01 each into ordinary shares of $0.025 each.

8.
Copies of the resolutions of the board of the Company approving, amongst other things, the Offering and the filing of the Registration Statement dated 4 June 2021 and 20 June 2021.

 
   
 
 
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Schedule 2

Assumptions

The opinions in this letter have been given on the basis of the following assumptions:

(i)
the genuineness of all signatures, stamps and seals on all documents, the authenticity and completeness of all documents submitted to us as originals, and the conformity to original documents of all documents submitted to us as copies;

(ii)
that, where a document has been examined by us in draft or specimen form, it will be or has been duly executed in the form of that draft or specimen, and that each of the signed documents examined by us has been duly executed and, where applicable, delivered on behalf of the Company;

(iii)
that the Completion Constitution will be so effective immediately prior to the issuance of the Additional Ordinary Shares and will not have been amended or superseded and that there will be no other terms governing the Additional Ordinary Shares other than those set out in the Completion Constitution;

(iv)
on the date of allotment and issue of the Additional Ordinary Shares (the “Allotment Date”) the Company will comply with all applicable laws to allot and issue the Additional Ordinary Shares;

(v)
that all documents, forms and notices which should have been delivered to the Registrar of Companies in respect of the Company have been so delivered, that information revealed by the Searches was complete and accurate in all respects and has not, since the time of the Searches, been altered and that the results of the Searches will remain complete and accurate as at the Allotment Date;

(vi)
that the minutes of the meetings of the board of directors of the Company and the written resolutions of the board of directors of the Company provided to us in connection with the giving of the opinions in this letter reflect a true record of the proceedings described in them in duly convened, constituted and quorate meetings in which all constitutional, statutory and other formalities were duly observed, and the resolutions set out in the minutes were validly passed and have not been and will not be revoked or varied and remain in full force and effect and will remain so as at the Allotment Date;

(vii)
that none of the resolutions of the shareholders of the Company upon which we have relied have been or will be varied, amended or revoked in any respect and remain in full force an effect;

(viii)
that, in relation to each meeting of the board of directors of the Company, each provision contained in the Companies Act 2014 (as amended (the “Companies Act”), the Constitution or the Completion Constitution relating to the declaration of the directors’ interests or the power of the interested directors to vote and to count in the quorum was or will be duly observed;

(ix)
that there is, at Allotment Date, no matter affecting the authority of the directors to issue and allot the Additional Ordinary Shares, not disclosed by the Completion Constitution or the resolutions produced to us, which would have any adverse implications in relation to the opinions expressed in this letter;

(x)
that the Additional Ordinary Shares offered under the 462(b) Registration Statement will be in consideration of the receipt by the Company prior to the issue of the Additional Ordinary Shares pursuant thereto of either cash or the release of a liability of the Company for a liquidated sum, at least equal to the nominal value of such Additional Ordinary shares and any premium required to be paid up on the Additional Ordinary Shares pursuant to their terms is issue;

 
   
 
 
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(xi)
that the 462(b) Registration Statement does not constitute (and is not intended/required to constitute) a prospectus within the meaning of Part 23 of the Companies Act and that no offer of securities to the public is made, or will be made, that requires the publication of a prospectus pursuant to Irish prospectus law in general, or in particular pursuant to the Prospectus (Directive 2017/1129) Regulations (EU) 2017/2019;

(xii)
that each party, to the extent that its activities in relation to the Offering will constitute the provision of an investment service operating in Ireland and require authorisation, is acting under and within the terms of an authorisation to do so (which authorisation has been given by the supervisory authority under the European Communities (Markets in Financial Instruments) Regulations (Nos. 1 to 3) 2007 or a competent authority for the purposes of Directive 2004/39/EC of 10 May 1993, as amended or extended from time to time, in another Member State) or is exempt from the requirement to have such authorisation;

(xiii)
that (i) the Company is at the date of this letter, and immediately after the issue of the Additional Ordinary Shares will be, able to pay its debts within the meaning of Sections 570 of the Companies Act or any analogous provisions under any applicable laws (ii) no liquidator, receiver or examiner or other similar or analogous officer has been appointed in relation to the Company any of the assets or undertakings; and (iii) no petition for the making of a winding-up order or the appointment of an examiner or any similar officer or any similar or analogous procedure in any jurisdiction has been presented in relation to the Company;

(xiv)
the accuracy and completeness of the information disclosed in the Searches and that such information is accurate as of the date of this letter and has not since the time of such search been altered. It should be noted that:

(A)
the matters disclosed in the Searches may not present a complete summary of the actual position on the matters we have caused searches to be conducted for;

(B)
the position reflected by the Searches may not be fully up-to-date (and this risk may be higher while emergency measures introduced by the Irish Government in light of the COVID-19 pandemic remain in place); and

(C)
searches at the Companies Registration Office, Dublin do not necessarily reveal whether or not a prior charge has been created or a resolution has been passed or a petition presented or any other action taken for the winding-up of, or the appointment of a receiver or an examiner to, the Company or its assets;

(xv)
the truth, completeness and accuracy of all representations and statements as to factual matters contained in the Documents; and

(xvi)
that all securities issued and sold under the 462(b) Registration Statement will be issued and sold in compliance with all applicable laws (other than Irish law), including applicable federal and state securities laws, in the manner stated in the Registration Statement.



Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We hereby consent to the incorporation by reference in this Registration Statement on Form F-1 of our report dated April 20, 2021 relating to the financial statements of GH Research Ireland Limited, which appears in Amendment No. 1 to the Registration Statement on Form F-1 (No. 333-256796) of GH Research PLC. We also consent to the reference to us under the heading “Experts” in Amendment No. 1 to the Registration Statement on Form F-1 (No. 333-256796) incorporated by reference in this Registration Statement.

/s/ PricewaterhouseCoopers SA
Lausanne, Switzerland
June 24, 2021